I use Nexguard for my dogs once a month I have noticed my dogs are itching sometimes in between treatments I have seen no fleas but sometimes my female will have redness inside her ears and on her belly. I have treated her for seasonal allergies with the Vet with Cytopoint Apaquel gave her bad diarrhea so that's a no go. I was wondering if the Nexguard could be causing some of this I have read some dogs were having reactions to the stuff was wondering if anyone else has seen anything similar. My male only itches a little and his ears are not red. I have always used the topical flea and tick until now so I am not sure whether I need to go back to that. I am a little leery of the ones that do heartworm and flea and tick. I use heartguard or Intercenpter plus for that. I live in a high tick zone area and we like to walk on the trails around here ticks have been really terrible this year I spray them Wondracide its made with cedar oil to repel flies and mosquitoes when we go out too but that's supposed to be all natural and non toxic. I keep them on heartworm stuff year round but usually stop the flea stuff when it gets cold.