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Discussion Starter #1
2008 REPORT ON RABIES VACCINE ADVERSE REACTIONS IN DOGS

The Journal of the American Veterinary Medical Association has published a report in its April 1, 2008 issue, Vol. 232, No. 7, entitled:  Postmarketing Surveillance of Rabies Vaccines for Dogs to Evaluate Safety and Efficacy."  

Despite the extreme under-reporting of vaccinal adverse reactions, this report states on the second page that between April 1, 2004 and March 31, 2007, the Center for Veterinary Biologics, "nearly 10,000 adverse event reports (all animal species) were received by manufacturers of rabies vaccines..........Approximately 65% of the manufacturer's reports involved dogs."

The report further states on the second page that: "Rabies vaccines are the most common group of biological products identified in adverse event reports received by the CVB," and they give the following description of the adverse reaction followed by the % of dogs affected:  Vomiting-28.1%, Facial Swelling-26.3%, Injection Site Swelling or Lump-19.4%, Lethargy-12%, Urticaria-10.1%, Circulatory shock-8.3%, Injection site pain-7.4%, Pruritus-7.4%, Injection site alopecia or hair loss-6.9%, Death-5.5%, Lack of Consciousness-5.5, Diarrhea-4.6%, Hypersensitivity (not specified)-4.6%, Fever-4.1%, Anaphylaxis-2.8%, Ataxia-2.8%, Lameness-2.8%, General signs of pain-2.3%, Hyperactivity-2.3%, Injection site scab or crust-2.3%, Muscle tremor-2.3%, Tachycardia-2.3%, and Thrombocytopenia-2.3%.

Veterinarians are not required by law to report adverse reactions to vaccines, to which the World Small Animal Veterinary Association stated in their 2007 Vaccine Guidelines that there is:  "gross under-reporting of vaccine-associated adverse events which impedes knowledge of the ongoing safety of these products," and in an article entitled, A New Approach to Reporting Medication and Device Adverse Effects and Product Problems, (JAMA - June 2, 1993. Vol.269, No.21. p.2785) Dr. David Kessler, former head of the Food & Drug Administration,  reported that "only about 1% of serious events are reported to the FDA."

In light of the 10,000 adverse reactions to the rabies vaccine in the JAVMA report, 65% of which were in dogs, the estimated 1% reporting of "serious" events by the former head of the FDA means that the actual number of dogs that had adverse reactions to the vaccine would be more like 650,000!!!!!

World Small Animal Veterinary Association 2007 Vaccine Guidelines http://www.wsava.org/SAC.htm Scroll down to Vaccine Guidelines 2007 (PDF)

A New Approach to Reporting Medication and Device Adverse Effects and Product Problems http://www.vaccinationnews.com/Adverse_Reactions/VAERS/credible_estimates.htm Scroll down to David Kessler statement in JAMA - June 2, 1993,vol.269, No.21, p.2785
 

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Re: 2008 RABIES Vaccine-JAVMA Report Adverse Reactions in Do

I guess my question is, if they don't get a rabies shot, what happens if they get bit by some animal with rabies ... sure death.  Do they need the shot every year?  I have no idea, but do I personally think it's necessary despite any reaction that could occur?  I do.
 

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Re: 2008 RABIES Vaccine-JAVMA Report Adverse Reactions in Do

After they have their one year booster for Rabies I think they only need it every three years after that.
 

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Discussion Starter #4
2 Doses Rabies Vax Protective according to CDC Study

Rabies immunization is required by law, so unless you are fortunate enough to live in a state which allows rabies titers in lieu of vaccination, you have no choice.

The following quote is from the Center for Disease Control's MMWR Recommendations and Reports March 22, 1991/40(RR03);1-19 Rabies Prevention-- United States, 1991 Recommendations of the Immunization Practices Advisory Committee http://www.cdc.gov/mmwr/preview/mmwrhtml/00041987.htm

"A fully vaccinated dog or cat is unlikely to become infected with rabies, although rare cases have been reported (48). In a nationwide study of rabies among dogs and cats in 1988, only one dog and two cats that were vaccinated contracted rabies (49). All three of these animals had received only single doses of vaccine; no documented vaccine failures occurred among dogs or cats that had received two vaccinations. " .

In 1992, a French research team led by Michel Aubert published results of a rabies challenge study (http://www.britfeld.com/rabies.htm) which demonstrated that dogs were immune to a rabies challenge 5 years after vaccination.  Dr. Ronald Schultz's serological studies (incorporated into the 2003, 2006 American Animal Hospital Association's Canine Vaccine Guidelines and 2007 World Small Animal Veterinary Association's Vaccine Guidelines) demonstrated that dogs had an antibody titer count at levels known to confer immunity to rabies 7 years after vaccination.

Dr. Schultz is currently conducting concurrent 5 & 7 year challenge studies on the canine rabies vaccine according to USDA vaccine-licensing guidelines with the goal is to extend the required interval for rabies boosters to 5 and then to 7 years.     For more information: http://www.rabieschallengefund.org/abou ... 20RCF.html .

Duration of Immunity to Canine Vaccines: What We Know and Don't Know, Dr. Ronald Schultz http://www.cedarbayvet.com/duration_of_immunity.htm

What Everyone Needs to Know about Canine Vaccines, Dr. Ronald Schultz http://www.puliclub.org/CHF/AKC2007Conf ... ccines.htm

World Small Animal Veterinary Association 2007 Vaccine Guidelines http://www.wsava.org/SAC.htm Scroll down to Vaccine Guidelines 2007 (PDF)

The 2003 American Animal Hospital Association's Canine Vaccine Guidelines are accessible online at http://www.leerburg.com/special_report.htm .

The 2006 American Animal Hospital Association's Canine Vaccine Guidelines are downloadable in PDF format at http://www.aahanet.org/PublicDocumen...s06Revised.pdf .

Veterinarian, Dr. Robert Rogers,has an excellent presentation on veterinary vaccines at http://www.newvaccinationprotocols.com/
 

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Re: 2008 RABIES Vaccine-JAVMA Report Adverse Reactions in Do

I live in Oklahoma and you have to have it done every year.  When I lived in Oregon it was every 3 years.
 

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Discussion Starter #6
Annual Rabies Laws

Rocky07,

You are aware of the efforts in Kansas and Wyoming to change their annual laws to the 3 year standard?  

Kansas:  http://www.boxerforums.com/modules.php?name=Forums&file=viewtopic&t=7741&highlight=kansas+rabies

Wyoming:  http://www.boxerforums.com/modules.php?name=Forums&file=viewtopic&t=8022&highlight=kansas+rabies

Perhaps dog owners in Oklahoma should get together and petition the state to adopt the national 3 year standard protocol, which is the recommendation of both the American Veterinary Medical Association  (AVMA) and the Center for Disease Control's National Association of State Public Health Veterinarians (NASPHV) that:  "Vaccines used in state and local rabies control programs should have at least a 3-year duration of immunity,"  and "All vaccines must be administered in accordance with the specifications of the product label or package insert." .

The quotes below are from an article in the (3/18/08) Wichita Eagle by Diane McCartney entitled:
Are annual shots a risk for dogs? Many wonder why city requires 3-year rabies vaccine yearly
http://www.kansas.com/news/story/344780.html  The following quotes are from that article:

Most veterinarians, including those in Wichita, use a rabies vaccine for dogs that is guaranteed by the U.S. Department of Agriculture to give immunity for three years.

That's why Michael Nawrocki, president of the Wichita Veterinary Medical Association, calls yearly rabies vaccinations "overkill."

"Every animal, whether they get the one-year or the three-year vaccine, it's the exact same vaccine; it's good for three years," Nawrocki said.

If the vaccine is good for three years, why does the city of Wichita require pets to be vaccinated every year?

Kay Johnson, director of the city's department of environmental services, says irresponsible pet owners are to blame.

Until we see better compliance with vaccinations in general, I'm not inclined to relax our position" on the yearly vaccine, she said.

"It's insane for them to go through this every year," said Christopher Hesse of College Hill Animal Hospital.

Requiring all dogs to be vaccinated annually because some people don't take their dogs in for shots is "ludicrous thinking," Hesse said.
 

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Re: 2008 RABIES Vaccine-JAVMA Report Adverse Reactions in Do

Actually neither the State of Oklahoma or the City of Lawton require annual rabies vaccination; I can't find the County ordinances online but it would be unusual for a city to have less-strict requirements than its governing county.

State
http://www.ok.gov/health/documents/Chap ... 20copy.pdf
The owner or custodian of a domestic dog, cat, or ferret shall cause the animal to be vaccinated against rabies by the time the animal is four months of age and at regular intervals thereafter according to the label directions of an approved rabies vaccine for use in that species, or as prescribed by ordinances or rules adopted by a municipality within whose jurisdiction the animal owner resides.

City
http://www.cityof.lawton.ok.us/CityCode ... 1/101.html
 

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Re: 2008 RABIES Vaccine-JAVMA Report Adverse Reactions in Do

I just called a couple vet offices and asked.  I was told yes in the state of Oklahoma it is annually.  So, I don't know..... :?
 

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Discussion Starter #9
Re: 2008 RABIES Vaccine-JAVMA Report Adverse Reactions in Do

Rocky07,

On Monday, call the City government where you live and find out from them what the ordinance or law is and ask them to give you the website address where you can access the language yourself.
 

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Re: 2008 RABIES Vaccine-JAVMA Report Adverse Reactions in Do

I lived in Oklahoma for a while and I know that you could buy your own rabies vaccine over the counter in farm stores.  Maybe you need to give your own when you want it.  Or maybe the vets are just wanting to give it every year for their reasons (money, ets)  I only vaccinate every 3 years here as required by the law.  I have had two boxers (both female, interesting..)that developed (IMT)  thrombocytopenia with no known cause and all ANA tests were negative.  I am convinced it was the rabies vaccine given annually that caused it in my two dogs.

I am hoping for the change of 5 - 7 years coming soon for everyone.  Is anything going on for change in North Carolina? I will have to check on that. We have a high number of rabies here due to all the wildlife in the mountains.

Nano
 

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Discussion Starter #12
Re: 2008 RABIES Vaccine-JAVMA Report Adverse Reactions in Do

nano,

I haven't heard about any efforts to change laws in North Carolina, but if I do, you'll see something about it posted on the forum.

Kris
 

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Discussion Starter #13
How Often Does He REALLY Need a Rabies Shot?--Link to Articl

More information specifically on the rabies vaccine can be found at the following links if you are interested to learn more:

Animal Wellness Magazine Article Vol. 8 Issue 6, How Often Does he REALLY Need A Rabies Shot   Animal Wellness Magazine - devoted to natural health in animals

The Rabies Challenge Animal Wise Radio Interview
Listen to Animal Wise  (scroll down to The Rabies Challenge 12/9/07)

The Vaccine Challenge Animal Talk Naturally Online Radio Show
 

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Discussion Starter #15
Re: 2008 RABIES Vaccine-JAVMA Report Adverse Reactions in Do

Arkansas Veterinary Medical Association http://www.arkvetmed.org/new.html
RABIES VACCINATIONS
New Recommendations


Recommendations for maintaining adequate pre-exposure immunization status: A routine booster every two years is NOT recommended since the newer cell culture vaccines often confer adequate antibody levels for 5 to 8 years and risk of adverse reactions is increased by frequent boosters. The standard pre-exposure recommendation for veterinarians practicing in an area with enzootic rabies is serologic testing every two years with booster vaccination when the antibody titer falls below the acceptable level, i.e. 1:5 by RFFIT.
 

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Discussion Starter #16
Vaccinal adverse reactions are becoming more recognized and acknowledged in the veterinary community -- in an August 1, 2008 article in DVM360 entitled Vaccination: An Overview, http://veterinarycalendar.dvm360.com/av ... ?id=568351 Dr. Melissa Kennedy states that of the two types of vaccinal adverse reactions:

Adverse reactions have also become a major concern in small animal medicine. .... These fall into two general categories. The first is immediate hypersensitivity. This may be a local or systemic response, and is due to pre-existing antibody to the agent. This is the classic "allergic reaction" to the vaccine and can be life-threatening. The second is a delayed response, requiring days of longer to develop. The vaccine, seen as foreign, elicits a significant inflammatory response and is especially true for adjuvanted vaccines. This response can manifest as a granuloma, or more seriously, a fibrosarcoma .

Further, she reports that The likelihood of adverse reactions in dogs has been found to correlate with the size of the dog and the number of inoculations given, with higher risk associated with small size and multiple inoculations.

___________________________________________

Duration of Immunity to Canine Vaccines: What We Know and Don't Know, Dr. Ronald Schultz http://www.cedarbayvet.com/duration_of_immunity.htm

What Everyone Needs to Know about Canine Vaccines, Dr. Ronald Schultz
http://www.puliclub.org/CHF/AKC2007Conf ... ccines.htm

Vaccination: An Overview Dr. Melissa Kennedy, DVM360 http://veterinarycalendar.dvm360.com/av ... ?id=568351

World Small Animal Veterinary Association 2007 Vaccine Guidelines http://www.wsava.org/SAC.htm Scroll down to Vaccine Guidelines 2007 (PDF)

The 2003 American Animal Hospital Association's Canine Vaccine Guidelines are accessible online at http://www.leerburg.com/special_report.htm .

The 2006 American Animal Hospital Association's Canine Vaccine Guidelines are downloadable in PDF format at http://www.aahanet.org/PublicDocumen...s06Revised.pdf .

Veterinarian, Dr. Robert Rogers,has an excellent presentation on veterinary vaccines at http://www.newvaccinationprotocols.com/

Duration of Immunity: The Rabies Vaccine Challenge - Show #185 Animal Talk Radio Show 7/30/08 http://www.blogtalkradio.com/animaltalk ... e-Show-186

October 1, 2002 DVM Newsletter article entitled, AVMA, AAHA to Release Vaccine Positions, http://www.dvmnewsmagazine.com/dvm/arti ... p?id=35171

July 1, 2003 DVM Newsletter article entitled, What Do We Tell Our Clients?, Developing thorough plan to educate staff on changing vaccine protocols essential for maintaining solid relationships with clients and ensuring quality care http://www.dvmnewsmagazine.com/dvm/arti ... p?id=61696

July 1, 2003, DVM Newsletter article, Developing Common Sense Strategies for Fiscal Responsibility: Using an interactive template to plan service protocol changes http://www.dvmnewsmagazine.com/dvm/article/articleDetail.jsp?id=61694

Animal Wellness Magazine Article Vol. 8 Issue 6, How Often Does he REALLY Need A Rabies Shot Animal Wellness Magazine - devoted to natural health in animals

The Rabies Challenge Animal Wise Radio Interview
Listen to Animal Wise (scroll down to The Rabies Challenge 12/9/07)

The Vaccine Challenge Animal Talk Naturally Online Radio Show » The Vaccine Challenge - Show #91

Rabies Shot Killed my Poodle May 28, 2008 Channel 5 News WCVB http://www.thebostonchannel.com:80/news ... os&taf=bos

US Declared Canine-Rabies Free -- CDC Announces at Inaugural World Rabies Day Symposium CDC Press Release - September 7, 2007

Rabies Prevention -- United States, 1991 Recommendations of the Immunization Practices Advisory Committee (ACIP), Center for Disease Control's Morbidity and Mortality Weekly March 22, 1991 / 40(RR03);1-19 http://www.cdc.gov/mmwr/preview/mmwrhtml/00041987.htm "A fully vaccinated dog or cat is unlikely to become infected with rabies, although rare cases have been reported (48). In a nationwide study of rabies among dogs and cats in 1988, only one dog and two cats that were vaccinated contracted rabies (49). All three of these animals had received only single doses of vaccine; no documented vaccine failures occurred among dogs or cats that had received two vaccinations. "
 

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We don't vaccinate our dogs. When we got our first dog (Luke) we vacinnated and he got so sick. It was horrible. He was throwing up and had hives all over him for about a week after. He had hives between his toes and under his paw pads and it was impossible to walk him. It took forever for us to get him better. I did alot of research on vaccines and after DH and I decided we would not do it again to him. Since his body has cleared out the drugs from his body he has been nothing but healthy! We would not vaccinate any of our dogs again. We titers test instead.
 

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Discussion Starter #18
Stunning photo, Totallyhip!

I follow Dr. Schultz's personal protocol and give my guys a distemper, hepatitis, and parvo shot separately after the age 14 weeks, then do a titer to see if they've had an immune response, and that's it. Rabies I have to do according to law, and I do have titers done for them to go into the boarding kennel for the first 3 diseases.

Kris
 

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Discussion Starter #19
Peaches' Story

Judy Schor's agility champion, Peaches, suffered a significant adverse reaction to a rabies booster. Judy has posted photos of Peaches and a letter from the vaccine manufacturer, Fort Dodge, offering a settlement to pay for medical treatment if they not disclose information about the claim. You can read the letter and see photos of Peaches at this link: http://www.facebook.com/album.php?aid=2042916&id=1447415540&ref=mf .
 

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Here in Pa. it's every three years after the initial one. Now I wonder if that is the reason Sunomi got so sick afer his shots. He was covered in hives and he almost died, the vet said it was a reaction to the Leptospirosis shot, but he has not been healthy since. Allergies, mange, ear infections, hair loss, you name it, he's probably had it. We have thousands of dollars in vet bills. He is just now starting to get hair back, but not all of it. And it has been almost a year. He's 18 months old today, and I think we have a long way to go.
 
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