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Curious what everyone uses on their boxers?

I used Frontline for a long time then switched to K9 Advantix 2, after fleas were found from Frontline. I noticed my girl last month lost fur on this topical treatment, last month a small clump of fur fell out a few inches away from treatment.
I was told by my vet to try Simperica, its a pill to chew. But I am concerned about some rare side effects such as tremors or seizures, which i read about after her appointment. I have not given to her yet.

I want everyone's opinions specifically on Simperica? This medicine goes into the blood stream vs. topical treatment. I am not interested in a flea collar like Soresto either. Thanks everyone!
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