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Well I don't know exactly where to begin. Me and my fiance have a Boxer she is roughly around 4-5 years old and has severe allergies/issues to just about everything. He purchased her at a local pet shop when she was a puppy and she was fine until she hit about 6 months old and has had problems ever since then. We have spent thousands on her to try and figure out the issues to no avail. She has been prescribed apoquel 16mg tablets 1-2x a day along with 6 benadryl (we have tried various other antihistamines as well), she has also been on prednisone which didn't work to well and she was constantly peeing all over the house because of it. We have also tried Cytopoint (sp) injection for allergy and she broke out in hives so bad she looked like bubble wrap for two weeks and had bloody stools. She gets bathed with a special prescription shampoo as well. She gets chronic ear infections and we can't get her ears to heal for the life of us. She has also been tested for allergies and it came back that she has a severe allergy to mites and fleas which we do use a product to prevent that. She shakes her head so much she is literally breaking open her ears on a daily basis, she will rub her face and chin on anything she can as well until she is bleeding and will continually lick her paws until they are red and raw. Our house is in a constant state of blood shed with her. We have changed her diet going through different proteins from chicken, beef, lamb, all types of fish, bison, kangaroo, grain free, canned, raw; and nothing is seeming to help her. Short of making her live in her e-collar forever and or be in a sedated state for the rest of her life we don't know what else to do with her. She is constantly miserable and we don't like having to continually yell at her and or use her e-collar to make her stop. Has anyone else had any success with any other treatments we are desperate.

Thanks
 

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Why are you yelling at her and using an e-collar?
She is in absolute constant discomfort.

Stress from constantly being yelled at or punished for scratching can also amplify her scratching simply due to stress.

You should ask for a referral to a dermatologist. Most dogs with severe allergies need combination medications. Apoquel & Cytopoint can be used together.
You might also want to try reaching out to a holistic vet and see about trying to reset her system naturally. Many have success with urine therapy as well.
Allergies stem from the gut. Heal and balance the gut and improve immune function.
 

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You didn't mention what you feed her, has she been on a completely raw diet? I don't know much about severe allergies other than some people are successful when feeding raw. Or is this strictly environmental. I too would have her see a dermatologist rather than a regular vet.
 

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A Dermatologist we saw for bad summer allergies said to try a food called Ultamino. We never did that so I can't comment. We did recently use Cytopoint shots, and it was amazing how the feet biting, and itching stopped within a couple days. The Apoguel never really fixed it. Right now, on the Cytopoint, we're seeing a flare of really red feet. The vet saw bacteria and yeast as the culprit, and has give us Keto-Med PS Antiseptic Wipes. They seem to be helping. The yard is full of pollen, and that's making it hard. I was told they could make up a monthly allergy shot for her if things persist.
 

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We had a home-cooked diet formulated for a Boxer who had severe IBD, and pancreatitis with eosinophillic enteritis. The BalaceIt mineral, amino-acid, and viitamin supplement that was mixed in the novel protein ingredients is hypoallergenic, and contains no animal proteins. I think that fixed things because the specialist thought any kind of preservative in proteins set him off. It was a fish diet.
 

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I agree that dog needs to see a dermatologist. It may be expensive at first but with all you have tried that has already been money out the door. I am surprised cytopoint did not help my dog did wonderful with it. Apaquel gave her bloody diarrhea. What kind of flea preventive is she on? Please don't yell at her, imagine you were itching all over and couldn't reach parts of your body to scratch. It sounds like there is something going on that keep tripping her allergies.
 

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On another note I just remembered when my dogs allergies got really bad I believe I was told that if it was a food allergy cytopoint and apaquel will not work. They have allergy diets by prescription available that have no allergens in them at all they are expensive and you must be disciplined to only using that food no treats or table food. She really needs that dermatologist
 

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From the allergies infections can happen with them rubbing their faces all over the house we just got back from the vet because of this her eyes matted up closed her tear ducts that got infected. This year has been really bad for allergies, apaquel helped a little and gave her bad diarrhea but had to go with the cytopoint shot to stop the itching. Benadryl helped some but now we are just waiting out the season with the cytopoint shot. Good luck finding the right solution!
 
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